While Tadalista 20 mg is generally safe for most men, alcohol consumption should be approached with caution. Moderate alcohol intake (like one or two drinks) may not significantly interfere with the effectiveness of the medication. However, drinking larger amounts of alcohol can increase the likelihood of side effects, such as headaches, dizziness, flushing, or low blood pressure. Alcohol can also reduce sexual performance and affect arousal, which may hinder the medication’s effectiveness.