Tadarise Black 80 mg is a medication commonly used to treat erectile dysfunction (ED). Its active ingredient is Tadalafil, a PDE5 inhibitor, which helps to improve blood flow to the penis during sexual stimulation, thus aiding in achieving and maintaining an erection. Tadalafil works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which is responsible for breaking down cyclic guanosine monophosphate (cGMP). cGMP plays a critical role in relaxing the smooth muscle in the blood vessels of the penis, allowing increased blood flow. By preventing the breakdown of cGMP, Tadalafil allows for a prolonged erection when there is sexual arousal.