what is a lip flip with botox Botox lip flips are a nonsurgical cosmetic treatment in which a medical expert injects a tiny quantity of Botox into the upper lip to make it seem larger. This article will explain what the lip flip process is, how it varies from using a dermal lip filler, and any potential problems to be aware of. Lip flips aren't permanent, so keep that in mind. Because only a little amount of Botox is injected into your lips, the results endure around 2 to 3 months. If you find that the effects are wearing off, you can choose to get further Botox injections to keep your results.